From I-75N & I-16E:

Merge onto I-16E from I-75N. Take Exit 1A/Spring St. off of I-16 immediately after merging. Turn right off of the exit ramp, merging onto Spring St. After crossing Walnut St., follow right-hand side of split and turn right onto Mulberry St. In two intersections, turn right on First Street. Follow First Street through the intersections of Cherry and Poplar streets. Macon CardioVascular Institute is on the right at the corner of Plum and First streets. Handicap entrance is in the back of the building.

From I-75S: Take Exit 164/Hardeman Ave. off of I-75. Turn right off of the exit ramp, merging onto Forsyth St. At the fourth traffic light (Spring Street), angle to the left. At the next light (A 6 way intersection with New Street), turn onto Plum Street. The Macon CardioVascular Institute entrance is on the left before the next traffic light. Handicap entrance is in the back of the building.